Mustansar Mubeen, Ashara Sajid, Yasir Iftikhar, Rana Binyamin, Muhammad A. Zeshan, Usman Saleem, Komal Ambreen, Muhammad U. Ghani


Cucumber mosaic disease (CMD), caused by cucmber mosaic virus (CMV) is the most devastating disease that can cause 100% losses in severe cases. CMV transmission is accomplished through mechanical or contact inoculation and sometimes through aphid in stylet borne manner. After entry into the host, CMV interrupts with normal physiology of cucumber plants resulting in mosaic patterns on leaves, reduction in leaf area leading to reduced yield. This review paper aims at assessment of yield losses caused by CMV, efficient disease diagnosis, finding the existing resistance sources and breeding potential for sustainable disease management. Various methods of diagnosis, symptomology, ecology, epidemiology and management tactics of CMV have been studied in this review. Usage of insecticides, for CMV management is not rational because it is occasionally transmitted through aphid and too in a non-persistent manner. The efforts for vector control even though through botanicals and organic oils is not as much effective due to quick virus transmission. CMV impairs the plant photosynthetic activity resulting in yield reduction, however the damages could be managed by using different nutrients. It is focused upon boosting the plant defense by using external application of different resistance inducing chemicals. CMV impairs the plant photosynthetic activity resulting in yield reduction, however the damages could be managed by using different nutrients. It is focused upon to boost the plant defense by using external application of different resistance inducing chemicals. Hence this review covers the aspects of ecofriendly management of CMV through genetic resistance and innovative cultural practices, which is the major future research area.


CMV, Pathogen, Host, Transmission, management, aphid, sap transmission

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Ahsan, M. and M. Ashfaq. 2018. First report of a Cucumber mosaic virus (CMV) subgroup II isolate infecting pea in Pakistan. Journal of Plant Pathology, 100(3): 597-597.

Akbar, A., Z. Ahmad, F. Begum and N. Raees. 2015. Varietal Reaction of Cucumber against Cucumber mosaic virus. American Journal of Plant Sciences, 6(07): 833.

Akhtar, K., K. Ryu, M. Saleem, M. Asghar, F. Jamil, M. Haq and I. Khan. 2008. Occurrence of Cucumber mosaic virus subgroup IA in tomato in Pakistan. Journal of Plant Diseases and Protection, 115(1): 2-3.

Akhtar, K. P., M.Y. Saleem, M. Asghar, M. Ahmad and N. Sarwar. 2010. Resistance of Solanum species to Cucumber mosaic virus subgroup IA and its vector Myzus persicae. European Journal of Plant Pathology, 128(4): 435-450.

Anderson, B. J., P. M. Boyce and C. L. Blanchard. 1995. RNA 4 sequences from Cucumber mosaic virus subgroups I and II. Gene, 161(2): 293-294.

Anfoka, G.H. 2000. Benzo-(1, 2, 3)-thiadiazole-7-carbothioic acid S-methyl ester induces systemic resistance in tomato (Lycopersicon esculentum. Mill cv. Vollendung) to Cucumber mosaic virus. Crop protection, 19(6): 401-405.

Anjum, S.A., L. Xue, L. Wang, M.F. Saleem and C.J. Huang. 2013. Exogenous benzoic acid (BZA) treatment can induce drought tolerance in soybean plants by improving gas-exchange and chlorophyll contents. Australian Journal of Crop Science, 7(5): 555.

Ashfaq, M., S. Iqbal, T. Mukhtar and H. Shah. 2014. Screening for resistance to Cucumber mosaic cucumovirus in chilli pepper. Journal of Animal and Plant Sciences, 24: 791-795.

Berke, T. 2002. The Asian vegetable research and development center pepper project. Paper presented at the Proceeding of the 16th International Pepper Conference Tampico. Tamaulipas, Mexico.

Chen, B., and R. Francki. 1990. Cucumovirus transmission by the aphid Myzus persicae is determined solely by the viral coat protein. Journal of General Virology, 71(4): 939-944.

Chen, Y.-K., R. Goldbachand M. Prins. 2002. Inter-and intramolecular recombinations in the Cucumber mosaic virus genome related to adaptation to alstroemeria. Journal of virology, 76(8): 4119-4124.

Chen, Y., J. Chen, H. Zhang, X. Tang and Z. Du. 2007. Molecular evidence and sequence analysis of a natural reassortant between Cucumber mosaic virus subgroup IA and II strains. Virus Genes, 35(2): 405-413.

Darzi, E., O. Lachman, E. Smith, A. Koren, E. Klein, N. Pass, O. Frenkel and A. Dombrovsky. 2020. Paths of Cucumber green mottle mosaic virus disease spread and disinfectant-based management. Annals of Applied Biology, 177: 374-384.

Doolittle, S. P. 1916. A new infectious mosaic disease of cucumber. Phytopathology, 6(2), 145-147.

Dragich, M., M. Melzer and S. Nelson. 2014. Cucumber mosaic virus in Hawaii. Plant Disease, 101: 1-10.

Dubey, V. K., and V. P. Singh. 2010. Molecular characterization of Cucumber mosaic virus infecting Gladiolus, revealing its phylogeny distinct from the Indian isolate and alike the Fny strain of CMV. Virus Genes, 41(1): 126-134.

Geetanjali, A. S., R. Kumar, P. Srivastava and B. Mandal. 2011. Biological and molecular characterization of two distinct tomato strains of Cucumber mosaic virus based on complete RNA-3 genome and subgroup specific diagnosis. Indian Journal of Virology, 22(2): 117.

Gera, A., G. Loebenstein and B. Raccah. 1979. Protein coats of two strains of Cucumber mosaic virus affect transmission by Aphis gossypii. Phytopathology, 69(4): 396-399.

Greber, R. 1978. Watermelon mosaic virus 1 and 2 in Queensland cucurbit crops. Australian Journal of Agricultural Research, 29(6): 1235-1245.

Gurjar, M. S., S. Ali, M. Akhtar and K. S. Singh. 2012. Efficacy of plant extracts in plant disease management. Agricultural Sciences, 3(3): 425.

Hellwald, K.-H., C. Zimmermann and H. Buchenauer. 2000. RNA 2 of Cucumber mosaic virus subgroup I strain NT-CMV is involved in the induction of severe symptoms in tomato. European Journal of Plant Pathology, 106(1): 95-99.

Hoggan, I. A. 1933. Some factors involved in aphid transmission of the Cucumber-mosaic virus to tobacco. Journal of Agricultural Research, 47, 689-704.

Hord, M. J., A. García, H. Villalobos, C. Rivera, G. Macaya and M. Roossinck. 2001. Field survey of Cucumber mosaic virus subgroups I and II in crop plants in Costa Rica. Plant disease, 85(9): 952-954.

Hosseinzadeh, H., S. Nasrollanejad and H. Khateri. 2012. Serological detection of Cucumber mosaic virus on some important host crops in the north region of Iran. Archives of Phytopathology and Plant Protection, 45(16): 1884-1890.

Iqbal, S., M. Ashfaq and H. Shah. 2011. Biological characterization of Pakistani isolates of Cucumber mosaic cucumovirus (CMV). Pakistan Journal of Botany, 43(6): 3041-3047.

Iqbal, S., M. Ashfaq and H. Shah. 2012. Prevalence and Distribution of Cucumber mosaic virus (CMV) in major Chilli Growing Areas of Pakistan. Pakistan Journal of Botany, 44(5): 1749-1754.

Jacquemond, M. 2012. Cucumber mosaic virus. Advances in Virus Research 84: 439-504. Elsevier.

Jalender, P., B. N. Bhat, K. Anitha and K. Vijayalakshmi. 2017. Survey for the Incidence of Cucumber mosaic virus in Tomato Growing Areas of Telangana and Andhra Pradesh. International Journal of Pure and Applied Bioscience, 5(4): 2058-2063.

Jones, R. and W. Proudlove. 1991. Further studies on Cucumber mosaic virus infection of narrow‐leafed lupin (Lupinus angustifolius): seed‐borne infection, aphid transmission, spread and effects on grain yield. Annals of Applied Biology, 118(2): 319-329.

Kähkönen, M. P., A. I. Hopia, H. J. Vuorela, J. P. Rauha, K. Pihlaja, T. S. Kujala and M. Heinonen. 1999. Antioxidant activity of plant extracts containing phenolic compounds. Journal of Agricultural and Food Chemistry, 47(10): 3954-3962.

Kaper, J. and H. Waterworth. 1977. Cucumber mosaic virus associated RNA 5: causal agent for tomato necrosis. Science, 196(4288): 429-431.

Khan, A., R. Sharma, B. Afreen, Q. Naqvi, S. Kumar, S. Snehi and S. Raj. 2011. Molecular identification of a new isolate of Cucumber mosaic virus subgroup II from basil (Ocimum sanctum) in India. Phytoparasitica, 39(2): 199-203.

Kim, M.-K., H. R. Kwak, S. G. Jeong, S. J. Ko, S. H. Lee, J. S. Kim and B. J. Cha. 2010. Characteristics of Cucumber mosaic virus infecting zucchini in Korea. The Plant Pathology Journal, 26(2): 139-148.

Kiranmai, G., P. Sreenivasulu and M. Nayudu. 1998. Epidemiology of Cucumber mosaic cucumovirus isolates naturally infecting three solanaceous vegetable crops around Tirupati. Indian Phytopathology, 51(4): 315-318.

Koundal, V., Q. M. R. Haq, and S. Praveen. 2011. Characterization, genetic diversity, and evolutionary link of Cucumber mosaic virus strain New Delhi from India. Biochemical Genetics, 49(1-2): 25-38.

Kumar, D., D. Chapagai, P. Dean and M. Davenport, M. 2015. Biotic and abiotic stress signaling mediated by salicylic acid. In Elucidation of abiotic stress signaling in plants (pp. 329-346). Springer, New York, NY.

Kumari, R., Bhardwaj, P., Singh, L., Zaidi, A. A., & Hallan, V. 2013. Biological and molecular characterization of Cucumber mosaic virus subgroup II isolate causing severe mosaic in cucumber. Indian journal of Virology, 24(1), 27-34.

Lee, J.-A., S. K. Choi, J. Y. Yoon, J. S. Hong, K. H. Ryu, S. Y. Lee and J. K.Choi. 2007. Variation in the pathogenicity of lily isolates of Cucumber mosaic virus. The Plant Pathology Journal, 23(4): 251-259.

Lobin, K. K., J. Svoboda, A. Lebeda, D. Y. Dhooky and S. P. Benimadhu. 2015. Cucumber mosaic virus causal pathogen of oily spots on cucumber cv. Locale fruits in Mauritius–short communication. Plant Protection Science, 51(3): 123-126.

Luo, Y., J. Zheng, T. Liu, W. Wang, Y. Huang, J. Shang and H. Yang. 2017. Identification and sequence analysis of a Cucumber mosaic virus isolate from solanum lycopersicum in South-West China. Journal of Plant Pathology, 99(2), 429-435.

Nishant, S., R. Kapoor, R. Kumar, S. Kumar, R.K. Saritha, S. Kumar, K. Virendra, Baranwal. 2019. Rapid diagnosis of Cucumber mosaic virus in banana plants using a fluorescence-based real-time isothermal reverse transcription-recombinase polymerase amplification assay. Journal of Virological Methods, 270: 52-58.

Nagendran, K., R. Priyanka, R. Aravintharaj, C.G. Balaji, S. Prashant, B. Basavaraj, S. Mohankumar and G. Karthikeyan. 2018. Characterization of Cucumber mosaic virus infecting snake gourd and bottle gourd in India. Physiological and molecular plant pathology, 103: 102-106.

Neergaard, P. 1977. Seed-borne viruses Seed Pathology, 71-117.

Oros G. and Z. Kállai. 2019. The constitutive defense compounds as potential botanical fungicides. In: Jogaiah S., Abdelrahman M., editors. Bioactive Molecules in Plant Defense. Springer; Cham, Switzerland: 2019. pp. 179-229.

Palukaitis, P., M. J. Roossinck, R. G. Dietzgen and R. I. Francki. 1992. Cucumber mosaic virus. Advances in Virus Research, 41: 281-348. Elsevier.

Pratap, D., S. Kumar and S. Raj. 2008. First molecular identification of a Cucumber mosaic virus isolate causing shoestring symptoms on tomato in India. Australasian Plant Disease Notes, 3(1): 57-58.

Raupach, G.S. and J.W. Kloepper. 1996. Biological control of Cucumber mosaic cucumovirus (CMV) in Cucumis Sativus L. By PGPR-Mediated Induced Systemic Resistance. Mitteilungen-Biologischen Bundesanstalt Fur Land Und Forstwirtschaft. 292-292.

Roossinck, M. J. 2001. Cucumber mosaic virus, a model for RNA virus evolution. Molecular Plant Pathology, 2(2): 59-63.

Roossinck, M. J. 2002. Evolutionary history of Cucumber mosaic virus deduced by phylogenetic analyses. Journal of Virology, 76(7): 3382-3387.

Schmelzer, K. 1957. Untersuchungen über den Wirtspflanzenkreis des Tabakmauche-Virus. Phytopathology, 30: 281-314.

Thackray, D., R. Jones, A. Bwye and B. Coutts. 2000. Further studies on the effects of insecticides on aphid vector numbers and spread of Cucumber mosaic virus in narrow-leafed lupins (Lupinus angustifolius). Crop Protection, 19(2), 121-139.

Tobias, I., B. Szabo, K. Salanki, L. Sari, H. Kuhlmann, L. Palkovics and M. Pitrat. 2008. Seedborne transmission of Zucchini yellow mosaic virus and Cucumber mosaic virus in Styrian Hulless group of Cucurbita pepo. In: Pitrat M. (ed.): Proceeding IXth EUCARPA Meeting of Genetics and Plant Breeding of Cucurbitaceae. INRA, Avignon: 189-197.

Waris, M., I. ul Haq, S. A. Khan, M. Iqbal, M. Shoaib and Z. Ullah. 2014. Screening of cucumber varieties against downy mildew (Pseudoperonospora cubensis) and its chemical management. Pakistan Journal of Phytopathology, 26(1): 21-24.

Yu, C., J. Wu and X. Zhou. 2005. Detection and subgrouping of Cucumber mosaic virus isolates by TAS-ELISA and immunocapture RT-PCR. Journal of Virological Methods, 123(2): 155-161.

Zhang, X., Y.R. Yuan, Y. Pei, S.S. Lin, T. Tuschl, D.J. Patel and N.H. Chua. 2006. Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. Genes & development, 20(23): 3255-3268.



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